赵丽;刘永宏;刘月焕;王凤龙;林健;韩春华;马明;丁玉林;丁旭娜;王金玲;杨龙峰;潘洁;韩婧雯;

• 1:内蒙古农业大学动物科学与医学学院
• 2:北京市农林科学院畜牧兽医研究所
• 3:中国农业大学动物医学院
• 4:北京市延庆县动物卫生监督管理局

摘要(Abstract)：

为了分析2009年新型A型H1N1流感病毒分子流行病学的特点,本文从NCBI上下载不同分离宿主的流感毒株各节段全基因序列应用分子生物学软件进行遗传演化分析,结果显示:新型A(H1N1)流感毒株与过去的人源A(H1N1)毒株相比差异较大,相对于此前的人源A(H1N1)流感毒株,HA出现了79个位点发生突变。其中14个是相对于所有来源A(H1N1)流感毒株的新突变位点,但有37个突变位点只能在猪源毒株中找到。究竟这一现象说明新型A(H1N1)流感毒株是猪、人源毒株的重组变异毒株,还是猪源H1N1感染人群后逐渐变异并适应人群的结果,还有待进一步研究。

关键词(KeyWords)： 甲型流感;序列;遗传演化分析

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 赵丽;刘永宏;刘月焕;王凤龙;林健;韩春华;马明;丁玉林;丁旭娜;王金玲;杨龙峰;潘洁;韩婧雯;

DOI: 10.13242/j.cnki.bingduxuebao.002062

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