樊毅,姜子义,李萍,邓益超,黄剑波,朱玲,徐志文

• 1:四川农业大学动物生物技术中心
• 2:四川农业大学动物疫病与人类健康四川省重点实验室

摘要(Abstract)：

中东呼吸综合征(Middle East respiratory syndrome,MERS)是由中东呼吸综合征冠状病毒(MERS Coronavirus,MERS-CoV)引起的一种呼吸系统疾病。目前该病已经蔓延到全球25个国家,造成1400余人感染,近500人死亡,并有4个国家报道骆驼感染MERS病例。研发相关疫苗成为预防该病非常重要的措施。研究人员在病毒载体、重组蛋白、DNAs、纳米粒子、MERS-CoV重组的基础上进行了大量的候选疫苗开发,其中一些还在实验动物身上进行了效果试验。本文就当前一些候选疫苗研究进展进行总结概括,以期更多人力物力投入到研发安全有效的疫苗当中。

关键词(KeyWords)： 中东呼吸综合征冠状病毒(MERS-CoV);中东呼吸综合征(MERS);动物模型;疫苗

Abstract:

Keywords:

基金项目(Foundation): 四川省科技支撑计划(项目号:2014NZ0043),题目:主要畜禽产品安全生产重大关键技术研究与示范;; 长江学者与创新团队发展计划(项目号:IRT13083),题目:川猪遗传改良与安全生产

作者(Author): 樊毅,姜子义,李萍,邓益超,黄剑波,朱玲,徐志文

DOI: 10.13242/j.cnki.bingduxuebao.003083

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