禽流感病毒样颗粒研究进展Progress in Development of Influenza Virus-Like Particles
戈胜强,王志亮
摘要(Abstract):
病毒样颗粒(Virus-like particles,VLPs)是指由病毒一个或几个结构蛋白自行组装成不含病毒基因组且不能复制、不具有感染能力的病毒样蛋白颗粒。VLPs因能够模拟天然病毒的构象表位而保持了完整病毒颗粒所具有的免疫原性,可诱导机体产生广泛强大的抗病毒免疫反应,阻止病毒侵入机体,在抗病毒性疾病的预防或治疗性疫苗及诊断试剂的研究开发方面具有巨大的应用前景。本文就禽流感病毒样颗粒相关研究进展进行综述,以期为我国禽流感VLPs的研究提供参考。
关键词(KeyWords): 禽流感;病毒样颗粒;疫苗
基金项目(Foundation):
作者(Author): 戈胜强,王志亮
DOI: 10.13242/j.cnki.bingduxuebao.002369
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