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疱疹性咽峡炎（Herpangina,HA）是一种由人肠道病毒（Enterovirus,EV）感染引起的急性传染性疾病，多发于6岁及以下儿童，该病以急性发热和咽颊部位疱疹为主要临床表现，其病原型别多样，一年四季均可发病，春夏季为主，其复杂的血清型变异导致疫苗研发困难，加之婴幼儿普遍易感的特性，现已成为威胁儿童健康的常见公共卫生问题。本文深入剖析了HA的流行特征、病原构成、临床表现、诊断及治疗方法，旨在提高相关机构和部门对HA的认知水平，通过加强疾病的监测、早期诊断与积极治疗，为预防和控制HA的发生与传播提供科学依据，促进早期预警与干预机制的建立，减轻家庭和社会的经济负担。
Abstract：Herpangina(HA) is an acute infectious disease caused by human enteroviruses(EVs), predominantly affecting children under the age of six. It is clinically characterized by sudden-onset fever and vesicular lesions in the pharyngeal and buccal mucosa. HA exhibits a wide range of causative serotypes and can occur year-round, with peak incidence in spring and summer. The extensive serotype variability poses significant challenges to vaccine development. Combined with the high susceptibility of infants and young children, HA has become a common public health concern impacting pediatric health. This review provides a comprehensive analysis of the epidemiological characteristics, etiological agents, clinical manifestations, diagnostic approaches, and treatment strategies for HA. It aims to enhance awareness among healthcare institutions and public health authorities, promote improved surveillance, early diagnosis, and timely clinical management, and offer scientific support for the prevention and control of HA outbreaks. Additionally, it advocates for the establishment of early warning and intervention mechanisms to reduce the economic burden on families and society.
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基本信息:
DOI：10.13242/j.cnki.bingduxuebao.250116
中图分类号:R766.12
引用信息:
[1]马雯晴,董祯,孙文魁,等.疱疹性咽峡炎：病原学、流行病学和防控策略[J].病毒学报,2025,41(06):1740-1748.DOI:10.13242/j.cnki.bingduxuebao.250116.
基金信息:
山东省医药卫生科技发展计划（项目号：202112050747）,题目：疫情常态化防控背景下山东省手足口病流行特征分析~~