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尼帕病毒（Nipah virus,NiV）是一种高致病性人兽共患病原体，主要在东南亚地区暴发流行，分为马来西亚株（NiV-M）和孟加拉国株（NiV-B）两个基因型。我国西南地区因存在该病毒自然宿主，存在输入性感染风险。NiV致死率居高不下，以血管损伤和神经系统病变为核心病理特征，快速精准的诊断技术是该病毒疫情防控的关键环节。本文综述NiV现有诊断技术及最新研究进展，为该病毒的疫情预警、临床诊断及防控工作提供技术参考。
Abstract：Nipah virus(NiV) is a highly pathogenic zoonotic pathogen that mainly causes outbreaks in Southeast Asia. It is classified into two genotypes: the Malaysia strain(NiV-M) and the Bangladesh strain(NiV-B). Due to the presence of its natural hosts in southwest China, there is a risk of imported infections. NiV is associated with an extremely high mortality rate, with vascular injury and neurological lesions as its core pathological features. Rapid and accurate diagnostic techniques are critical for the prevention and control of NiV outbreaks. This paper reviews the existing diagnostic technologies and recent research advances in NiV, aiming to provide technical references for early warning, clinical diagnosis, and prevention and control of NiV infections.
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基本信息:
DOI：10.13242/j.cnki.bingduxuebao.260092
中图分类号:R373
引用信息:
[1]艾丽孜热·艾力,陈芳娟,高晨,等.尼帕病毒检测技术研究进展[J].病毒学报,2026,42(04):1085-1092.DOI:10.13242/j.cnki.bingduxuebao.260092.
基金信息:
国家重点研发计划（项目号：2023YFC2605602）,题目：高致病性病毒遗传进化特征与溯源关键技术研究~~
2026-03-18
2026
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