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埃博拉病毒能在人类和非人灵长类中引起严重的埃博拉出血热,病死率可高达90%,并且目前还没有针对埃博拉病毒有效的疫苗或者是治疗手段。面对埃博拉病毒带来的挑战,针对埃博拉病毒的相关研究已经成为病毒学的热点问题。其中,关于埃博拉病毒侵染细胞机制的科学研究对于开发病毒疫苗以及新型治疗药物有非常关键的作用。因此,本综述拟就埃博拉病毒侵染细胞机制方面的研究进展进行总结。
Abstract:Ebola virus can cause severe Ebola hemorrhagic fever.The mortality rate is 90 percent.Up till now,there is no effective vaccine or treatment of Ebola virus infection.Relaed researches on Ebola virus have become a hot topic in virology.The understanding of molecular mechanisms of Ebola virus infection of cells are important for the development of vaccine and anti-virus drugs.Therefore,this review summarized the recent research progress on the mechanisms of Ebola virus infection.
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基本信息:
DOI:10.13242/j.cnki.bingduxuebao.002354
中图分类号:R373.9
引用信息:
[1]石明,沈宇清.埃博拉病毒侵染细胞机制的研究进展[J].病毒学报,2013,29(01):71-75.DOI:10.13242/j.cnki.bingduxuebao.002354.
基金信息:
东南大学教学改革研究项目(2010-079);; 东南大学大学生科研训练(SRTP)项目(11412003)