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2017, 06, v.33 932-937
寨卡病毒新型疫苗的研究进展
基金项目(Foundation): 国家重点研发计划(项目号:2016YFD0500300,2016YFC1200900);题目:重大突发动物源性人兽共患传染病跨种感染与传播机制研究,重要新发突发病原体防治、处置技术与产品研究; 国家科技重大专项"十三五"计划(项目号:2016ZX10004001-003);题目:传染病应急疫苗研究~~
邮箱(Email):
DOI: 10.13242/j.cnki.bingduxuebao.003249
发布时间: 2017-10-19
出版时间: 2017-10-19
网络发布时间: 2017-10-19
移动端阅读
摘要:

寨卡病毒(Zika virus,ZIKV)感染可造成胎儿小头症及成人格林巴利综合症,世界卫生组织已将其定为世界公众健康紧急事件。因此急需要发展新型Zika疫苗。本文简要介绍寨卡病毒生物学性状、流行病学、临床表现,并重点对寨卡病毒3种新型疫苗(DNA、病毒载体、mRNA疫苗)研究进展进行综述与应用展望。

Abstract:

The Zika virus(ZIKV)has been associated with microcephaly in fetuses and the Guillain-Barrésyndrome in adults.The World Health Organization has declared it to be a worldwide healthy emergency.The development of a safe and effective ZIKV vaccine is,therefore,an urgent global health priority.We made a brief introduction about the virology,epidemiology and symptoms of ZIKV,with major emphasis on the recent advances of three novel vaccine candidates(DNA vaccine,viral-vector vaccine,mRNA vaccine)against ZIKV.We also highlighted the development and application of a vaccine against ZIKV.

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基本信息:

DOI:10.13242/j.cnki.bingduxuebao.003249

中图分类号:R392

引用信息:

[1]詹瑛,邓瑶,谭文杰.寨卡病毒新型疫苗的研究进展[J].病毒学报,2017,33(06):932-937.DOI:10.13242/j.cnki.bingduxuebao.003249.

基金信息:

国家重点研发计划(项目号:2016YFD0500300,2016YFC1200900);题目:重大突发动物源性人兽共患传染病跨种感染与传播机制研究,重要新发突发病原体防治、处置技术与产品研究; 国家科技重大专项"十三五"计划(项目号:2016ZX10004001-003);题目:传染病应急疫苗研究~~

发布时间:

2017-10-19

出版时间:

2017-10-19

网络发布时间:

2017-10-19

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